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Read MoreThe ameloblastoma, first reported as an "odontome" in 1827, has long been known as one of the most unusual and complex of odontogenic tumors, with a variety of clinical and microscopic types (Table 1) [1,2]. By 1928 it became clear that this benign, locally aggressive neoplasm with its large growth potential had an additional unique feature.
In contrast to alopecia related to conversion of terminal hairs to vellus hairs on a genetic/hormonal basis, Alopecia Areata (AA) is considered to have an inflammatory basis with psychogenetic and possible genetic contribution. Thus, most treatments that have been tried for AA have been attempts to interrupt the inflammatory pathways.
Non-Small Cell Lung Cancer (NSCLC) frequently harbors actionable genetic alterations, including RET fusions, which occur in 1–2% of cases, predominantly in adenocarcinomas. Selpercatinib, a selective RET inhibitor, has significantly improved outcomes in these patients, demonstrating high response rates even following prior therapies.
The purpose of this review and perspective is to discuss the most recent reviews of causation and treatment, with the goal of conception, of women with diminished ovarian reserve and Premature Ovarian Failure (POF). The perspective part of this review will provide our opinion on the suggested etiologies.
Though the presence of bone pain is common in children with Acute Lymphocytic Leukemia (ALL), it is uncommon in adults. A case is presented where CT-scan to evaluate back pain led to a biopsy and diagnosis of ALL. Though 95% of the marrow was replaced by lymphoblasts, perhaps this early diagnosis was the reason why all blood hematologic parameters were completely normal.