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About Us

International journal of clinical and medical case studies (ISSN: 3067-3852)

International Journal of Clinical and Medical Case Studies is a peer-reviewed, open-access journal that focuses on the publication of insightful, real-world case studies that contribute to the advancement of medical science and clinical practice. By highlighting unique and rare clinical cases, the journal provides healthcare professionals and researchers with the opportunity to share critical observations and medical breakthroughs, fostering a deeper understanding of complex conditions.

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Latest Articles

Review Article

The relationship between diminished ovarian reserve and the increased cellular permeability syndrome

Jerome H Check, MD, PhD; Madison Neulander, BS; Diane L Check, BS; Megan McDonald-O'Neil, MS; Carrie Wilson BS

The purpose of this review and perspective is to discuss the most recent reviews of causation and treatment, with the goal of conception, of women with diminished ovarian reserve and Premature Ovarian Failure (POF). The perspective part of this review will provide our opinion on the suggested etiologies.

Case Report

Adult B-cell acute lymphocytic leukemia associated with osteolysis, but normal hematologic parameters – Rare case or related to treatment with mifepristone

Jerome H Check, MD, Phd*

Though the presence of bone pain is common in children with Acute Lymphocytic Leukemia (ALL), it is uncommon in adults. A case is presented where CT-scan to evaluate back pain led to a biopsy and diagnosis of ALL. Though 95% of the marrow was replaced by lymphoblasts, perhaps this early diagnosis was the reason why all blood hematologic parameters were completely normal.

Short Commentary

Non-carious lesions: A modern condition that can affect teeth

Carolina dos Santos Santinoni*; Ana Paula Varela Brown Martins; Juliana Silva Ribeiro De Andrade; Mauricio Malheiros Badaró; Sheila Cristina Stolf Cupani; Thais Mageste Duque

The decrease in the prevalence of caries and periodontal disease, as well as the aging of the world's population, has increased the number of cases of diseases unrelated to the presence of microorganisms, such as cervical dentin hypersensitivity and Non-Carious Lesions (NCL) [1].

Short Commentary

Dental management of HIV positive patients

Carolina dos Santos Santinoni*; Gabriel Leonardo Magrin; Bernardo Born Passoni; Ariadne Cristiane Cabral da Cruz; Marco Aurélio Bianchini; Gláucia Santos Zimmermann; Cesar Augusto Magalhães Benfatti; Ricardo de Souza Magini

The medications used by these patients can cause side effects, manifestations in the oral cavity and interact with drugs used by the dentist, interfering with the dental treatment plan [1]. Antiretrovirals (ARVs) are used not only to treat the infection but also as a strategy to prevent it in various situations.

Research Article

How nitroxide-restricted endothelial function contributes to the development of acute lung abscess

Muhammad Salman Malik; Abu Huraira; Abdul Rehman; Muhammad Abuzar Fahim; Abdullah Bin Aamer; Arsalan Khalid; Hira Ashiq; Muhammad Waqar Mazhar*

Among the leading causes of infection and mortality worldwide, purulent-destructive lung diseases continue to rank high. Impairment of this organ's barrier-filtration function, based on endothelial dysfunction, may be connected with the key to infection development in acute lung abscesses.

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